Pretty consistent with mainstream browsers (Chrome, FF, Safari), apart from one apparent issue with Safari, described in details here with no super-clean solution yet.
Another notable exception is IE\Edge, that sometimes applies random colors, and makes standard elements such as dropdowns, or scrollbars look horrible 
Also, the OS used affects how elements are looking like (Dropdowns, Scroll Bars).
There’s also an issue with retina displays, that sometimes makes the font size and icons look weird (too big, while looking ok on non-retina displays).
From functional standpoint - we did not see any differences in behaviour of workflows or any other logic within the applications (as it’s done on the server-side anyways).
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